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A white laboratory rodent perched on the edge of a blue-toned glass container, possibly a test tube or a beaker

We are the leading Preclinical Neuroscience CRO specializing in rodent models of CNS diseases

We focus on providing services leveraging the best available models of ALS, Alzheimer’s Disease, Multiple Sclerosis, and Parkinson's Disease


Rodent Models

Learn more about our thoroughly characterized and validated models of CNS diseases

We have a range of transgenic and inducible models readily available for your studies. Our team of animal model scientists will work with you to find the right model.

Amyotrophic Lateral Sclerosis (ALS)

TDP-43 mouse models with cytoplasmic aggregates, motor dysfunction, neurodegeneration, neuroinflammation, and neuromuscular changes.

Amyotrophic Lateral Sclerosis (ALS)

TDP-43 mouse models with cytoplasmic aggregates, motor dysfunction, neurodegeneration, neuroinflammation, and neuromuscular changes.

Alzheimer's Disease

β-amyloid and tau models with progressive pathologic changes in a well-defined spatiotemporal pattern.

Multiple Sclerosis (MS)

EAE, cuprizone, and other models that recapitulate the autoimmune inflammation, demyelination & remyelination, and neurodegeneration aspects of human disease.

Parkinson's Disease

α-synuclein preformed fibril (PFF) seeding & spreading models recapitulating different aspects of Parkinson's disease.

Our Services

We provide a range of specialized research services tailored to models of CNS diseases

End-to-end services from model generation to in-life testing to quantitative tissue & fluid biomarkers.

A close-up of a medical syringe with a needle inserted into a small vial, likely a therapeutic agent

Animal Services

Our animal services team are experts in dosing via multiple routes of administration, stereotaxic surgical procedures, and fluid & tissue collection.

Behavioral Testing - a three-dimensional maze with high walls, and within this maze, there's a white laboratory mouse looking out from one of the corridors.

Behavioral Testing

We use specific, validated tests that are sensitive to response to therapy in our CNS rodent models.

A digital rendering of a neuron, which is a cell that transmits nerve impulses.


We use well-established, in vivo electrophysiological measures to evaluate motor and sensory function.

A close-up of test tubes in a laboratory setting with a pipette dispensing a liquid into one of them

Fluid & Cellular Biomarkers

We can measure clinically translational biomarkers, such as neurofilament light, in blood and cerebrospinal fluid (CSF). We can also perform cellular immunophenotyping on a range of tissues, including brain, spinal cord, lymph nodes, and spleen.

A series of MRI (Magnetic Resonance Imaging) brain scans displayed on a light box or a digital screen

Histology & Tissue Analysis

We have a state-of-the-art histopathology facility specializing in tissues collected from rodent models of neurological diseases.

In Vivo Imaging of mouse brain

In Vivo Imaging

We use preclinical MRI, PET, and CT scanners, coupled with our advanced image processing & analysis techniques, to non-invasively measure changes in brain & muscle structure (e.g. atrophy) and function (e.g. metabolism, blood flow).

Our Latest Innovations

Narrated presentations of our scientific advancements

Contact Us

Let us know what you’re interested in. Our team will be happy to discuss with you!

Email us at i[email protected] or simply complete & submit the form below. 

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