Our Services
We provide a range of specialized research services tailored to models of CNS diseases
End-to-end services from model generation to in-life testing to quantitative tissue & fluid biomarkers.
- Animal Services
- Behavioral Testing
- Electrophysiology
- Fluid & Cellular Biomarkers
- Histology & Tissue Analysis
- In Vivo Imaging
![A close-up of a medical syringe with a needle inserted into a small vial, likely a therapeutic agent](https://bspuatstorageaccount.blob.core.windows.net/publicstrapiuploads/MediaLibrary/Animal_Services_Our_Services_Landing_Page_4f30e23ae3.webp)
![Behavioral Testing - a three-dimensional maze with high walls, and within this maze, there's a white laboratory mouse looking out from one of the corridors.](https://bspuatstorageaccount.blob.core.windows.net/publicstrapiuploads/MediaLibrary/Behavioral_Testing_Our_Services_Landing_Page_f01b6866e2.webp)
![A digital rendering of a neuron, which is a cell that transmits nerve impulses.](https://bspuatstorageaccount.blob.core.windows.net/publicstrapiuploads/MediaLibrary/Electrophysiology_Our_Services_Landing_Page_cc29eb1220.webp)
![A close-up of test tubes in a laboratory setting with a pipette dispensing a liquid into one of them](https://bspuatstorageaccount.blob.core.windows.net/publicstrapiuploads/MediaLibrary/Fluid_and_Cellular_Biomarkers_Our_Services_Landing_Page_0d9ef67f5f.webp)
![A series of MRI (Magnetic Resonance Imaging) brain scans displayed on a light box or a digital screen](https://bspuatstorageaccount.blob.core.windows.net/publicstrapiuploads/MediaLibrary/Histology_and_Tissue_Analysis_e3f8e06026.webp)
Our Latest Innovations
Narrated presentations of our scientific advancements
Microglial Activation in an α-Synuclein Mouse Model of Parkinson’s Disease
Leveraging computer vision and machine learning algorithms, we have quantified microglial activation in immunohistochemistry (IHC) sections from an α-synuclein preformed fibril (PFF) seeding & spreading mouse model.
β-Amyloid & the Inflammatory Microenvironment in an APP/PS1 Mouse Model of Alzheimer’s Disease
By applying advanced image analysis techniques to multiplex immunofluorescence data, we have been able to explore spatiotemporal changes in the inflammatory microenvironment of β-amyloid plaques in an APP/PS1 transgenic model.
Brain Atrophy Analysis in Rodent Models of Neurodegeneration
Brain atrophy is a hallmark of many neurodegenerative diseases. MRI is routinely used in clinical trials to non-invasively measure volumetric and cortical thickness changes. We have applied these translational imaging biomarkers to mouse models of ALS and Parkinson’s disease.