Preclinical WebsiteClinical Website

Computerized Tomography (CT)

While preclinical CT is not typically as widely used as MRI or PET for imaging mouse models of CNS diseases, we have found it to be very effective for muscle imaging.

CT scans provide good muscle-to-bone contrast and high-resolution (<100 µm), isotropic images of muscles of the forelimbs and hindlimbs. Scans can typically be acquired in <20 minutes (including animal positioning). 

CT - Mouse leg muscles Scan

We are one of the few groups in the world that can generate fully-automated, CT-based muscle atrophy measures. Our NIGHTWING™ software platform is capable of segmenting mouse and rat muscles and computing volumetric measures.

Longitudinal evaluation of muscle atrophy can be particularly useful in models of neuromuscular diseases and models with abnormal innervation due to misfolded proteins.

CT - Mouse leg muscles Segmentation Scan

Learn more about our Computerized Tomography (CT) Services.

Discover more of our In Vivo Imaging Services


Why use CT for muscle imaging?

CT has an advantage of providing higher resolution images in a shorter period of time compared to MRI or PET. As such, it is a cost-effective modality for evaluation of muscle atrophy (e.g. hindlimb muscle volume measures).

Does Biospective use CT for rodent brain imaging?

We acquire CT images as part of our PET scanning protocol for anatomical localization and co-registration to MRI scans. However, we do not typically acquire CT scans of brain alone, as MRI has superior brain contrast compared to CT.

Can CT scanning of muscles in different parts of the rodent's body be performed?

Yes. While the hindlimb muscles are typically evaluated for atrophy in rodent models of CNS diseases, we can perform CT imaging of different muscle groups. 

More Information

Let us know what you’re interested in. Our team will be happy to discuss with you!

Email us at i[email protected] or simply complete & submit the form below. 

Phone Number*
Affiliation (Company/University)*

Your privacy is important to us. We will protect your data as outlined in our Privacy Notice.

I agree to the terms in the Privacy Notice*

We use necessary cookies to make our site work. We also use other cookies to help us make improvements by measuring how you use the site or for marketing purposes. You have the choice to accept or reject them all. For more detailed information about the cookies we use, see our Privacy Notice.