α-Synuclein Fibril Seeding Model (Limbic System)
Injection of α-synuclein PFFs into the Anterior Olfactory Nucleus (AON) to generate a Parkinson's disease mouse model with altered sleep, brain atrophy, and neuroinflammation.
α-Synuclein Fibril Seeding Model (Motor System)
Injection of α-synuclein PFFs into the motor system to generate a Parkinson's disease mouse model with dopaminergic dysfunction.