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α-Synuclein Fibril Seeding Model (Limbic System)

Injection of α-synuclein PFFs into the Anterior Olfactory Nucleus (AON) to generate a Parkinson's disease mouse model with altered sleep, brain atrophy, and neuroinflammation.

A pair of brain tissue sections processed with immunohistochemistry (IHC) to highlight phosphorylated alpha-synuclein, which is relevant in the context of Parkinson's Disease research

α-Synuclein Fibril Seeding Model (Motor System)

Injection of α-synuclein PFFs into the motor system to generate a Parkinson's disease mouse model with dopaminergic dysfunction.

Immunohistochemistry (IHC) staining of brain tissue sections to reveal alpha synuclein burden in anterior olfactory nucleus (AON), associated with Parkinson's Disease (PD)

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