Stereotaxic Surgery

We can deliver therapeutic agents directly into the CNS. We use digital stereotaxic devices with automated microinjectors for a high degree of accuracy and reproducibility. Stereotaxic procedures (injections, catheterizations) are used for intracerebral (i.c.) and intracerebroventricular (i.c.v.) administration of therapeutics agents.

We have extensive experience with delivery of viral vectors, antibodies, antisense oligonucleotides, and small molecules.  

We can generate rodent models via stereotaxic procedures. We can deliver recombinant proteins (e.g. α-synuclein and tau preformed fibrils), viral vectors (e.g. AAVs), human brain extracts (e.g. patient-derived extracts), and neurotoxins.