We typically collect blood and cerebrospinal fluid (CSF) as part of our CNS rodent model studies. These fluids can be collected both in-life and at the terminal endpoint. Blood and CSF samples can be analyzed for drug concentrations or various biomarkers, such as neurofilament light (NfL), a marker of neurodegeneration.
We can provide collected samples back to our Sponsors for their in-house analysis.
Collection of brain, spinal cord, and skeletal muscle is a routine service in our CNS rodent model studies. Tissues can be snap frozen for drug concentration analysis, biochemistry, proteomics, etc.Tissues can also be fixed and frozen or fixed and paraffin-embedded for immunohistochemistry and/or immunofluorescences studies.
At Biospective, we have a state-of-the-art histopathology lab for tissue analysis.
Learn more about our Fluid & Tissue Collection Services.
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Can Biospective perform in-life CSF collection?
Yes. Our team has developed special expertise to collect CSF from mice and rats during the in-life phase of the study.
Can Biospective collect urine & feces from rodent models?
Yes. We can collect urine samples and fecal pellets for analysis.
Can Biospective collect peripheral tissues/organs?
Yes. We can collect tissues/organs, such as spleen, lymph nodes, lungs, kidneys, colon, etc. These organs can be frozen or fixed & paraffin-embedded.