Table of Contents
Iba-1 Stain Density
Iba-1 stain density in ipsilateral (Ipsi) and contralateral (Contra) piriform (PIR) and entorhinal (ENT) cortices, as well as the CA1 region of the hippocampus. Statistical analysis was performed using Kruskal-Wallis non-parametric test and Dunn's multiple comparisons test. Data from PBS- and PFF-injected mice are shown at 2, 3, and 4 months post-injection.
Activated Microglia Density
Activated microglia density in ipsilateral (Ipsi) and contralateral (Contra) piriform (PIR) and entorhinal (ENT) cortices, as well as the CA1 region of the hippocampus. Statistical analysis was performed using Kruskal-Wallis non-parametric test and Dunn's multiple comparisons test. Data from PBS- and PFF-injected mice are shown at 2, 3, and 4 months post-injection.
Early pathologic changes in the contralateral entorhinal cortex. Iba-1 IHC staining from mice at 2 months after PBS (left) and PFF (right) injections. The blue and red boxes in the images indicate microglia that were classified as non-activated and activated, respectively.