Table of Contents
Cells showing progressively higher activation score (from 0 to 1) from left to right. These cells show progressive changes in their morphology, supporting the use of this score as a metric of activation.
An example of how the model arrives at a decision using the Shapley (SHAP) values, and how the value of each features contribute toward an activation score.
In this example (cell shown in inset), the large soma, high number of branches, and low soma circularity contribute the most towards a high activation score. The value of each parameter (normalized to the average) is shown in gray and the positive SHAP values (shown in red) tend towards the activated state.
For example, low soma circularity (lower than average in this case) contributes towards activation. The SHAP values for each feature are summed to obtain the overall SHAP value for that particular cell.