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Classification of activated microglia (red boxes) in the hippocampus at 3 months post-injection of PBS (top left) and human α-synuclein PFFs (top right) into the anterior olfactory nucleus.
In the low magnification view (bottom), we can readily appreciate the quantity and distribution of activated microglia (red boxes) in the ipsilateral and contralateral hemispheres of the PFF-injected mice at the level of the entorhinal cortex and posterior hippocampus.