Table of Contents
Abstract
01. Presentation OverviewPresentation
01. Introduction02. Neuroinflammation Classification03. Microglial Activation04. Plaque Microenvironment05. AD Mouse Model06. Age & Amyloid07. Age & Neuroinflammation08. Age & Microglial Activation09. Microenvironment Analysis10. Age & Inflammatory Microenvironment11. SummaryA complex spatiotemporal relationship exists between amyloid-β & neuroinflammation in Alzheimer's disease
Multiplex immunofluorescence (IF) demonstrating Iba-1 positive microglia and GFAP positive astrocytes intimately associated with β-amyloid plaques, as well as distributed outside of the local neighborhood of these plaques.