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Age-dependent changes in activated microglia density (A) and GFAP stain density (B) inside amyloid plaques ("local") in the cerebral cortex of ARTE10 mice compared to levels not associated with plaques ("global") in wild-type mice. N=10-12 per group. Statistical analysis was performed using Kruskal-Wallis non-parametric test and Dunn’s multiple comparisons test. *p<0.05; **p<0.005; ***p<0.001; ****p<0.0001.
Age-dependent changes in activated microglia density (A) and GFAP stain density (B) not locally associated with amyloid plaques in the cerebral cortex of ARTE10 and WT mice. N=10-12 per group. Statistical analysis was performed using Kruskal-Wallis non-parametric test and Dunn’s multiple comparisons test. *p<0.05; **p<0.005; ***p<0.001; ****p<0.0001.