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Example MRI scans (axial, sagittal, coronal views) from the rNLS8 mouse model. The images from control mice are shown on the left, while the images from Off Dox mice are shown on the right. The arrows identify regions of high signal, representing regional atrophic cortex.
The bottom panel shows the cortical thickness streamlines superimposed on the sagittal images. Note that we exclude the high CSF signal and only measure thickness in the cortex.